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Código SKU: PKSM041430_10μg-ES
Receptor de tirosina quinasa neurotrófica de ratón recombinante tipo 2/TrkB/NTRK2 (C-6His), 10 μg
La familia TRK del receptor de tirosina quinasa consta de tres miembros: TrkA, TrkB y TrkC. Las tres proteínas de la familia TRK tienen diferentes especificidades de ligando. Se unen a diferentes neurotrofinas, como NGF, BDNF y NT-3/NT-4/5. TRKA se une a NGF, TRKB a BDNF y NT-3, y TRKC a NT-4/5. A nivel de secuencia proteica, TRKB humano y de rata presentan una identidad de secuencia superior al 90% y exhiben actividad interespecífica. TRKB se expresa principalmente en el sistema nervioso y también se expresa en una amplia variedad de tejidos con niveles bajos.
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