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Código SKU: PKSM041017_50μg-ES
Proteína heterodímera recombinante de ratón FcRn y B2M (etiqueta His), 50 μg
El complejo FcRn consta de dos subunidades: la subunidad grande p51 del receptor de IgG FcRn (cadena alfa) y la beta-2-microglobulina (cadena beta). Los complejos son similares en estructura al heterodímero similar al MHC clase I. La beta-2-microglobulina participa en la presentación de antígenos peptídicos al sistema inmunitario. El FcRn se une a la región Fc de las inmunoglobulinas monoméricas gamma, media la captación de IgG de la leche y tiene un posible papel en la transferencia de inmunoglobulina G de la madre al feto. Un componente principal del transporte de anticuerpos es el receptor neonatal para la porción Fc de la inmunoglobulina, un heterodímero de un homólogo de la cadena alfa del MHC-1 (FcRn) y la beta-2-microglobulina (B2M).
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Brands:Elabscience
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