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Código SKU: PKSH033198_10μg-ES
Proteína uroplaquina-2/UPK2 humana recombinante (etiqueta His), 10 μg
La uroplaquina-2 es una proteína de membrana de tipo I de un solo paso que pertenece a la familia de las uroplaquinas-2. Es un componente de la membrana unitaria asimétrica (UMA) y se expresa en el uréter, una biomembrana altamente especializada elaborada por células uroteliales terminalmente diferenciadas. La uroplaquina-2 forma un heterodímero con UPK1A, necesario para su salida del retículo endoplasmático (RE). La uroplaquina-2 podría desempeñar un papel importante en la regulación del ensamblaje de la MUA. Se cree que la MUA fortalece el urotelio al prevenir la ruptura celular durante la distensión vesical.
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