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Código SKU: PKSH033197_50μg-ES
Proteína UPP1 humana recombinante (etiqueta His), 50 μg
La uridinafosforilasa 1 (UPP1) pertenece a la familia de las pentosiltransferasas. La UPP1 cataliza la fosforólisis reversible de la uridina a uracilo. Los niveles de expresión y la actividad enzimática de la UPP1 son mayores en tumores sólidos humanos que en tejidos normales adyacentes. Su alta expresión en algunos tumores la convierte en un posible factor pronóstico para ciertos tipos de cáncer, como el carcinoma escamocelular oral. La UPP1 es importante para la regulación homeostática de las concentraciones intracelulares y plasmáticas de uridina. Desempeña un papel importante en la vía de rescate de pirimidinas mediante la catálisis de la fosforólisis reversible de la uridina a uracilo.
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