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Código SKU: PKSH032817_50μg-ES
Proteína humana recombinante ULBP2/N2DL-2 (etiqueta Fc), 50 μg
El ligando 2 de NKG2D (N2DL2) pertenece a una familia de proteínas de superficie celular. N2DL2 funciona como ligando de la glucoproteína UL16 del citomegalovirus humano. N2DL2 se ancla a la membrana mediante un enlace GPI. N2DL2 se une al NKG2D humano, un receptor activador expresado en células NK, células NKT y células T. La interacción de NKG2D activa la actividad citolítica y la producción de citocinas en estas células. Los ULBP se expresan en algunas células tumorales y se han implicado en la vigilancia tumoral.
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