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Código SKU: PKSH033367_50μg-ES
Proteína UBE2D1 humana recombinante (etiqueta GST), 50 μg
La enzima conjugadora de ubiquitina E2 D1 (UBE2D1) pertenece a la familia de las enzimas conjugadoras de ubiquitina. La ubiquitinación implica al menos tres clases de enzimas: enzimas activadoras de ubiquitina (E1); enzimas conjugadoras de ubiquitina (E2); y ligasas de ubiquitina-proteína (E3). Esta enzima está estrechamente relacionada con un estimulador del transporte de hierro (SFT) y se regula positivamente en la hemocromatosis hereditaria. También participa en la ubiquitinación de la proteína supresora de tumores p53 y del factor de transcripción inducible por hipoxia HIF1α, al interactuar con la enzima activadora de ubiquitina E1 y las ligasas de ubiquitina-proteína E3.
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