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Código SKU: PKSH033044_10μg-ES
Proteína SerpinH1/SERPINH1 humana recombinante (etiqueta His), 10 μg
La serpina H1 es un inhibidor de la serina proteinasa que pertenece a la familia de las serpinas. Se induce por choque térmico. Se localiza en el lumen del retículo endoplasmático y se une específicamente al colágeno. Por lo tanto, se cree que es una chaperona molecular que participa en la maduración de las moléculas de colágeno. Se han encontrado autoanticuerpos contra esta proteína en pacientes con artritis reumatoide. La serpina H1 podría ser un marcador de cáncer, y los polimorfismos de nucleótidos en este gen podrían estar asociados con el parto prematuro causado por la rotura prematura de membranas.
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