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Código SKU: PKSH033017_50μg-ES
Proteína semaforina 3C/SEMA3C humana recombinante (etiqueta His), 50 μg
La semaforina 3C es una de las seis semaforinas secretadas de clase 3, potentes quimiorrepelentes que intervienen en la guía axonal y/o vascular durante el desarrollo y que pueden ser sobreexpresadas durante la progresión tumoral. La semaforina 3C consta de una secuencia señal de 20 aminoácidos, un dominio Sema N-terminal, un nudo de cisteína, un sitio de escisión de tipo furina, un dominio similar a Ig y un dominio básico C-terminal. La semaforina 3C presenta una alta expresión en corazón, colon, músculo esquelético, intestino delgado, testículos, ovario y próstata, y una baja expresión en otros órganos, incluido el cerebro.
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