Código SKU: PKSH033335_10μg-ES

Proteína SECTM1 humana recombinante (etiqueta His), 10 μg

La proteína secretada y transmembrana 1 (SECTM1) es una proteína transmembrana y secretada que pertenece a la familia SECTM. SECTM1 se expresa con un patrón perinuclear similar al del Golgi. Se detecta en niveles máximos en leucocitos de sangre periférica y líneas celulares de cáncer de mama. Se considera que SECTM1 participa en la señalización de los timocitos y en los procesos del sistema hematopoyético/inmunitario. Se ha descrito que SECTM1 es una molécula ampliamente expresada, inducible por IFN-γ, que funciona como un potente ligando coestimulador para la activación de linfocitos T y presenta sinergia con anti-CD28.

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