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Código SKU: PDMH100235_100μg-ES
Proteína PTX3 humana recombinante (etiqueta Fc), 100 μg
Ptx3, también conocido como secuencia génica 14 estimulada por el factor de necrosis tumoral (TSG14), es un receptor de reconocimiento de patrones secretado que desempeña un papel no redundante en la resistencia a ciertos agentes microbianos. Ptx3 pertenece a la familia de las pentraxinas largas, que poseen dominios de pentraxina C-terminales y nuevos dominios amino-terminales. Ptx3 se une a patógenos seleccionados, como Aspergillus fumigatus, Pseudomonas aeruginosa y Salmonella typhimurium. Se sintetiza en la glomerulonefritis por IgA y activa las células mesangiales.
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