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Código SKU: PDEH101010_20μg-ES
Proteína humana recombinante PP2A-Cα/PPP2CA (etiqueta His), 20 μg
La proteína fosfatasa 2A (PP2A) es una enzima que elimina los fosfatos unidos covalentemente a los residuos de serina y treonina en las proteínas. Contiene tres subunidades: una subunidad catalítica C (PP2Ac), una subunidad de ensamblaje/estructural A (PP2Aa) y una subunidad reguladora B (PP2Ab). La PP2A es una enzima ubicua que participa en la regulación de numerosas actividades celulares, desde el transporte de iones en los eritrocitos hasta la supresión del crecimiento tumoral. Se sabe que la unión del antígeno T pequeño SV40 al complejo fosfatasa PP2A causa transformación oncogénica.
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