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Código SKU: PKSH032958_10μg-ES
Proteína PDIA6 humana recombinante (etiqueta His), 10 μg
La proteína disulfuro isomerasa A6 (PDIA6) es una proteína de 48,5 kDa que pertenece a la familia de las proteínas disulfuro isomerasas (PDI). PDIA6 es una enzima del retículo endoplasmático en eucariotas que cataliza la formación y rotura de enlaces disulfuro entre los residuos de cisteína dentro de las proteínas durante su plegamiento. La PDIA6, expresada en plaquetas, funciona como una chaperona que inhibe la agregación de proteínas mal plegadas. PDIA6 forma parte de un gran complejo multiproteico de chaperona que comprende DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1 y UGT1A1. PDIA6 también participa en la agregación plaquetaria y su activación por agonistas como la convulxina, el colágeno y la trombina.
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