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Código SKU: PKSH032796_50μg-ES
Proteína neurocalcina-δ/NCALD humana recombinante (etiqueta His), 50 μg
La neurocalcina delta (NCALD) es una proteína neuronal transportadora de calcio que pertenece a la familia de los sensores neuronales de calcio (NCS). Se expresa en cerebros de mamíferos. NCALD contiene una señal de miristoilación N-terminal y cuatro bucles de unión al calcio con manos EF. La proteína posee un interruptor Ca₂/miristoílo. Es citosólica en niveles de calcio en reposo. Sin embargo, niveles elevados de calcio intracelular inducen un cambio conformacional que expone el grupo miristoílo, lo que resulta en la asociación de la proteína con las membranas y la colocalización parcial con la red trans-Golgi perinuclear. Se cree que la proteína NCALD regula la transducción de señales del receptor acoplado a proteína G.
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