Código SKU: PKSH033881_50μg-ES

GDF-8/miostatina recombinante humana/de ratón/de rata, 50 μg

El factor de crecimiento/diferenciación 8 (Mstn, GDF-8) pertenece a la familia de las proteínas morfogenéticas óseas (BMP) y a la superfamilia TGF-beta. Este grupo de proteínas se caracteriza por un sitio de procesamiento proteolítico polibásico que se escinde para producir una proteína madura que contiene siete residuos de cisteína conservados. Se expresa específicamente en el músculo esquelético en desarrollo y adulto. Existe como homodímero e interactúa con WFIKKN2, inhibiendo su actividad. Esta proteína puede actuar específicamente como regulador negativo del crecimiento del músculo esquelético. Regula el crecimiento y la diferenciación celular tanto en tejidos embrionarios como adultos.

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