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Código SKU: PKSH034171_20μg-ES
Proteína MMP7 humana recombinante (N-His), 20 μg
La proenzima metaloproteinasa de matriz 7 (proMMP-7) es una metaloproteinasa de matriz de 30,47 kDa con 273 residuos de aminoácidos. La MMP-7 restringe su producción en las células epiteliales normales de las mucosas y las glándulas exocrinas, así como en las células carcinomatosas. Funcionalmente, participa en la degradación de la matriz extracelular (caseína, gelatinas de tipos I, III, IV y V, y fibronectina) en procesos fisiológicos normales y patológicos. La MMP-7 contribuye al desarrollo tumoral temprano durante la carcinogénesis. La activación de la proMMP7 por tripsina se produce a través de un intermediario escindido en Lys50-Asn51.
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