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Código SKU: PKSH030834_100μg-ES
Proteína humana recombinante LMAN2/VIP36 (E. coli, etiqueta His), 100 μg
La lectina de tipo L LMAN2 (también conocida como VIP36) parece ser específicamente necesaria para la acumulación de GPRC5B en el complejo de Golgi y la restricción de su transporte a lo largo de la vía exosomal. Esto podría deberse a la interferencia con el transporte de GPRC5B de la red trans de Golgi al endosoma, mediado por la proteína adaptadora GGA1. Una vía que atraviesa el Golgi para la liberación exosomal de la proteína de carga GPRC5B, en la que CD2AP facilita la entrada y LMAN2 impide la salida del flujo, respectivamente.
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