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Código SKU: PKSH031964_100μg-ES
Proteína humana recombinante LILRB4/CD85k/ILT3 (aa 1-257, etiqueta Fc), 100 μg
El receptor tipo inmunoglobulina leucocitaria (LILR) B4 pertenece a una familia de receptores de superficie celular que posee motivos inhibidores basados en tirosina (ITIM) del inmunorreceptor citoplasmático. Se cree que LILRB4 inhibe las señales de activación mediadas por cascadas de tirosina quinasas no receptoras mediante el reclutamiento de SHP-1. LILRB4 se asocia con los procesos patológicos de diversas enfermedades inflamatorias. LILRB4 es un receptor inhibidor central en las células dendríticas uterinas (CDU) que desempeña funciones esenciales de inmunorregulación en la interfaz materno-fetal.
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