Código SKU: PKSH030460_50μg-ES

Proteína LAG3/CD223 humana recombinante (etiqueta Fc), 50 μg

LAG3, también conocido como CD223 y gen 3 de activación linfocítica, pertenece a la superfamilia de las inmunoglobulinas (Ig). LAG3 contiene cuatro dominios extracelulares similares a Ig. El gen LAG3 contiene ocho exones. Se expresa selectivamente en células T y NK activadas. LAG3 tiene una función reguladora negativa en las células T. También actúa como un nuevo marcador de la activación de células B inducida por células T. Como molécula soluble, LAG3 activa las células presentadoras de antígenos mediante la señalización del MHC de clase II, lo que aumenta la respuesta de las células T específicas de antígeno in vivo.

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