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Código SKU: PDMH100378_20μg-ES
Proteína IGFBP3 humana recombinante (etiqueta His), 20 μg
Las proteínas de unión a IGF prolongan la vida media de los IGF y se ha demostrado que inhiben o estimulan sus efectos promotores del crecimiento en cultivos celulares. Alteran la interacción de los IGF con sus receptores de superficie celular. También presentan efectos antiproliferativos y apoptóticos independientes de IGF, mediados por su receptor TMEM219/IGFBP-3R. Inhiben el efecto positivo de la humanina sobre la sensibilidad a la insulina. Promueven la apoptosis de células germinales testiculares.
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