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Código SKU: PKSH033429_50μg-ES
Proteína IFNGR1 humana recombinante (etiqueta His), 50 μg
El receptor de interferón gamma 1 (IFNGR1), codificado por el gen IFNGR1, es una proteína de membrana de un solo paso tipo 1 que pertenece a la familia de receptores de citocinas tipo II. El IFNGR1 se fosforila en los residuos Ser/Thr tras la traducción. El IFNGR1 es un receptor para el interferón gamma; dos receptores se unen a un dímero de interferón gamma. Una variación genética en el IFNGR1 se asocia con la susceptibilidad a la infección por Helicobacter pylori. Además, los defectos en el IFNGR1 son causa de la susceptibilidad mendeliana a la enfermedad micobacteriana, también conocida como infección micobacteriana atípica diseminada familiar.
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