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Código SKU: PKSH033618_50μg-ES
Proteína humana recombinante IFN-λ3/IL-28B, 50 μg
La interleucina-28B, también conocida como citocina Zcyto22, interferón lambda-3, interferón lambda-4, IFNL3, IFNL4, ZCYTO22 e IL28B, es una citocina secretada que pertenece a la familia IL-28/IL-29. Se ha demostrado que la IL-28 también participa en la respuesta inmunitaria adaptativa. La IL28B posee actividad inmunomoduladora y regula positivamente la expresión del antígeno MHC de clase I. Presenta una potente actividad antiviral y antitumoral. Además, la IL28B es un ligando del receptor heterodimérico de citocinas de clase II, compuesto por IL10RB e IL28RA. El complejo ligando/receptor parece señalizar a través de la vía Jak-STAT.
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