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Código SKU: PDMH100033_100μg-ES
Proteína GITRL humana recombinante (etiqueta His), 100 μg
Citocina que se une a TNFRSF18/AITR/GITR. Regula la respuesta de los linfocitos T. Puede actuar como coestimulador y reducir el umbral de activación y proliferación de los linfocitos T. Es importante para las interacciones entre los linfocitos T activados y las células endoteliales. Media la activación de NF-κB. Incrementa la fosforilación de STAT1 y regula positivamente la expresión de VCAM1 e ICAM1. Promueve la adhesión leucocitaria a las células endoteliales. Regula la migración de monocitos desde el reservorio esplénico a los focos de inflamación.
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Brands:Elabscience
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