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Código SKU: PKSH032427_10μg-ES
Proteína humana recombinante FGFR5/FGFRL1 (etiqueta His), 10 μg
El receptor tipo 1 del factor de crecimiento de fibroblastos (FGFRL1) es una proteína de membrana de tipo I de un solo paso que pertenece a la familia de receptores de FGF. El FGFRL1 humano maduro consta de un dominio extracelular (ECD) de 354 aminoácidos con tres dominios de tipo C2 similares a Ig, un segmento transmembrana de 21 aminoácidos y un dominio citoplasmático de 134 aminoácidos. El FGFR1 se expresa en diversos tejidos, principalmente en el cartilaginoso y el páncreas. Presenta una alta expresión en hígado, riñón, corazón, cerebro y músculo esquelético, y una expresión débil en pulmón, intestino delgado y bazo. El FGFRL1 tiene un efecto negativo sobre la proliferación celular.
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