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Código SKU: PKSH032391_10μg-ES
Proteína humana recombinante Ephrin-A4/EFNA4 (etiqueta His), 10 μg
La efrina-A4 pertenece a la familia de ligandos de efrina y se une a miembros de la familia de receptores Eph. Todos los ligandos comparten una secuencia extracelular conservada, que probablemente corresponde al dominio de unión al receptor. La efrina-A4 consta de aproximadamente 125 aminoácidos e incluye cuatro cisteínas invariantes. Se ha demostrado que se une a EphA2; EphA3; EphA4; EphA5; EphA6; EphA7; y EphB1. La efrina-A4 se une promiscuamente a los receptores Eph que residen en células adyacentes, lo que produce una señalización bidireccional dependiente del contacto hacia las células vecinas. Podría desempeñar un papel en la interacción entre los linfocitos B activados y las células dendríticas de las amígdalas.
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