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Código SKU: PKSH033569_50μg-ES
Proteína ciclofilina B/PPIB humana recombinante (etiqueta His), 50 μg
La ciclofilina B (SCYLP, CyPB y peptidil-prolil cis-trans isomerasa B) es una glicoproteína de 24 kDa de la subfamilia B de las PPIasas de tipo ciclofilina. Se secreta y retiene en el RE. Al secretarse, la ciclofilina B media la quimiotaxis y la adhesión de linfocitos T a la fibronectina. Esto probablemente se deba a su actividad como prolil cis/trans isomerasa. A nivel intracelular, la ciclofilina B parece actuar como chaperona molecular para las moléculas destinadas a la secreción. Esto se logra mediante la estabilización y facilitando la actividad de chaperonas adicionales.
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