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Código SKU: PKSH032243_10μg-ES
Proteína humana recombinante CGREF1/CGR11 (etiqueta His), 10 μg
El regulador del crecimiento celular con dominio EF-Hand, proteína 1 (CGREF1), es una proteína secretada que se une a iones de calcio. CGREF1 contiene dos dominios EF-Hand, ambos necesarios para su función. El CGREF1 humano se sintetiza como un precursor de 301 aminoácidos que contiene una secuencia señal de 19 aminoácidos y una cadena madura de 282 aminoácidos. Es probable que CGREF1 sea digerido extracelularmente por una serina proteasa desconocida, generando péptidos bioactivos extremadamente hidrofóbicos. CGREF1 media la adhesión intercelular de forma dependiente del calcio. Además, CGREF1 es capaz de inhibir el crecimiento en varias líneas celulares.
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