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Código SKU: PDEH100885_20μg-ES
Proteína CCL28 humana recombinante (etiqueta His), 20 μg
El ligando 28 de quimiocina (motivo CC) (CCL28) es una quimiocina novedosa que comparte la mayor homología con CCL27/CTACK. CCL28 muestra actividad quimiotáctica para linfocitos T CD4+ y CD8+ en reposo y eosinófilos. Se une a CCR3 y CCR10 e induce la movilización de calcio de forma dosis-dependiente. CCR10 (receptor huérfano GPR2) también es el receptor para CCL27/CTACK. CCL28 se expresa preferentemente en células epiteliales de diversos tejidos, con el mayor nivel de expresión en colon normal y patológico. También se expresa en tejidos pulmonares normales y asmáticos. El CCL28 humano y murino comparte un 83% de identidad de secuencia en sus regiones maduras.
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