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Código SKU: PKSH032140_10μg-ES
Proteína Cadherina-3/CDH3 Humana Recombinante (His Tag), 10 μg
La cadherina-3 (CDH3) es una proteína de membrana de tipo I de un solo paso que pertenece a la superfamilia de las cadherinas. La CDH3 es una glicoproteína de adhesión intercelular dependiente de calcio, compuesta por cinco repeticiones extracelulares de cadherina, una región transmembrana y una cola citoplasmática altamente conservada. La CDH3 se expresa en algunos tejidos epiteliales normales y en algunas líneas celulares de carcinoma. La CDH3 interactúa preferentemente consigo misma de forma homofílica en las células conectivas. La CDH3 participa en la pérdida de heterocigosidad en el cáncer de mama y de próstata. Las mutaciones en la CDH3 se han asociado con hipotricosis congénita y distrofia macular juvenil.
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