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Código SKU: PKSH032136_50μg-ES
Proteína Cadherina-11/CDH11 Humana Recombinante (His Tag), 50 μg
La cadherina-11 es una cadherina clásica de tipo II, miembro de la superfamilia de las cadherinas, proteínas integrales de membrana que median la adhesión intercelular dependiente del calcio. Las cadherinas interactúan entre sí de forma homofílica en la conexión celular, contribuyendo así a la clasificación de tipos celulares heterogéneos. La cadherina-11 contiene cinco dominios de cadherina y se expresa principalmente en el cerebro. Las proteínas cadherinas maduras constan de un gran dominio extracelular N-terminal; un único dominio transmembrana; y un pequeño dominio citoplasmático C-terminal altamente conservado. Se ha demostrado que la cadherina-11 es una diana molecular viable para la intervención terapéutica en el glioblastoma multiforme.
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