Código SKU: PDEH100609_100μg-ES

Proteína APOA4 humana recombinante (etiqueta Sumo), 100 μg

La apolipoproteína está genéticamente asociada con el riesgo de enfermedad de Alzheimer (EA). Los genes APOA1, APOC3 y APOA4 están estrechamente vinculados y se localizan en el cromosoma 11. Se observó una tendencia a la disminución de los niveles de APOA1, APOC3 y APOA4 en pacientes con EA. CONCLUSIÓN: Los niveles bajos de APOA1, APOC3 y APOA4 se asocian con el riesgo de EA. APOA1, APOC3 y APOA4 deberían desarrollarse como fármacos combinados para el tratamiento de la EA. Los SNP (polimorfismos de un solo nucleótido) en los genes APOA1 y APOA4 influyen en las características aterogénicas de las partículas LDL en respuesta a la dieta.

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