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Código SKU: PKSR030494_10μg-ES
Proteína ACE2 humana recombinante (etiqueta mFc), 10 μg
La enzima convertidora de angiotensina 2 (ECA-2) es una proteína integral de membrana y una metaloproteasa de zinc de la familia de las ECA, que incluye la ECA somática y germinal. La ECA-2 escinde las angiotensinas I y II como carboxipeptidasa, convierte la angiotensina I en angiotensina 1-9 y la angiotensina II en angiotensina 1-7. También hidroliza la apelina-13 y la dinorfina-13 con alta eficiencia. La ECA-2 puede expresarse en niveles elevados en testículos, riñones y corazón, y en niveles moderados en colon, intestino delgado y ovario. El captopril y el lisinopril, inhibidores clásicos de la ECA, no inhiben la actividad de la ECA-2. La ECA-2 puede desempeñar un papel importante en la regulación de la función cardíaca.
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