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Código SKU: E-AB-53322_120μL-ES
Anticuerpo policlonal RAC2, 120 μL
RAC2, también denominada GX, pertenece a la superfamilia de las GTPasas pequeñas y a la familia Rho. RAC2 es una GTPasa pequeña asociada a la membrana plasmática que alterna entre un estado activo unido a GTP y uno inactivo unido a GDP. En estado activo, se une a diversas proteínas efectoras para regular las respuestas celulares, como los procesos secretores, la fagocitosis de células apoptóticas y la polarización de las células epiteliales. RAC2 aumenta la producción de especies reactivas de oxígeno (ROS) por la NADPH oxidasa. Los defectos en RAC2 son la causa del síndrome de inmunodeficiencia de neutrófilos.
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