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Código SKU: E-AB-F1043J_20T-ES
Anticuerpo anti-CD54 humano PerCP/Cyanine5.5 [15.2], 20 T
CD54 es una proteína transmembrana tipo I de 85-110 kD, también conocida como ICAM-1. Se expresa en células endoteliales activadas, vénulas endoteliales altas, linfocitos T y B, monocitos/macrófagos, granulocitos y células dendríticas. La expresión de ICAM-1 puede liberarse desde la superficie celular. CD54 participa en la adhesión celular y participa en la inflamación y la extravasación leucocitaria. También se ha demostrado que CD54 es el principal receptor celular del rinovirus. ICAM-1 se une a CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150, 95), así como al hialuronano y al fibrinógeno.
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