Código SKU: E-AB-F1068G_100T-ES

Anticuerpo anti-CD58 humano PE/Cyanine5 [TS2/9.1], 100 T

El CD58, también conocido como antígeno 3 asociado a la función linfocítica (LFA-3), es una proteína de superficie celular de 45-70 kD que pertenece a la superfamilia de las inmunoglobulinas. El empalme alternativo del CD58 da lugar a formas transmembrana y ancladas al glicosilfosfatidilinositol (GPI) en la superficie celular. El CD58 se expresa tanto en células hematopoyéticas como no hematopoyéticas, incluyendo linfocitos B, linfocitos T, monocitos, eritrocitos, células endoteliales, células epiteliales y fibroblastos. Se observan niveles elevados en linfocitos T de memoria y células dendríticas. El CD58 expresado en células presentadoras de antígenos y células diana mejora el reconocimiento de los linfocitos T mediante la unión de su ligando cognado, CD2, en la superficie del linfocito T.

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