Código SKU: E-AB-F1067I_20T-ES

Anticuerpo anti-CD57 humano PE/Cyanine5.5 [HNK-1], 20 T

El CD57, también conocido como HNK-1, NK-1 y Leu-7, es un determinante antigénico oligosacárido de 100-115 kD que se expresa en diversas proteínas, lípidos y proteoglicanos de sulfato de condroitina. El CD57 se expresa en un subgrupo de linfocitos de sangre periférica, como las células NK y los linfocitos T CD8+, y también en células neuronales y músculo estriado. No se expresa en eritrocitos, granulocitos, monocitos ni plaquetas. Si bien se desconoce la función del CD57, su unión a la L-selectina, la P-selectina y un fragmento de laminina sugiere que podría estar involucrado en las interacciones célula-matriz. El CD57 aumenta en algunas enfermedades asociadas con desequilibrios de CD4/CD8 (SIDA, enfermedades autoinmunes, infecciones virales y trasplantes de aloinjertos).

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