Código SKU: E-AB-93037_120μL-ES

Anticuerpo policlonal MMP9, 120 μL

Las proteínas de la familia de las metaloproteinasas de matriz (MMP) participan en la degradación de la matriz extracelular en procesos fisiológicos normales, como el desarrollo embrionario, la reproducción y la remodelación tisular, así como en procesos patológicos como la artritis y la metástasis. La mayoría de las MMP se secretan como proproteínas inactivas que se activan al ser escindidas por proteinasas extracelulares. La enzima codificada por este gen degrada los colágenos de tipo IV y V. Estudios en monos rhesus sugieren que la enzima participa en la movilización de células progenitoras hematopoyéticas de la médula ósea inducida por IL-8, y estudios murinos sugieren un papel en la remodelación tisular asociada a tumores.

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