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Código SKU: E-AB-68249_120μL-ES
Anticuerpo policlonal IGF1R (validado por KO), 120 μL
Este receptor se une al factor de crecimiento similar a la insulina con alta afinidad. Posee actividad de tirosina quinasa. El receptor del factor de crecimiento similar a la insulina I desempeña un papel crucial en los procesos de transformación. La escisión del precursor genera subunidades alfa y beta. Presenta una alta sobreexpresión en la mayoría de los tejidos malignos, donde actúa como agente antiapoptótico al mejorar la supervivencia celular. Se han encontrado variantes de transcripción con empalme alternativo que codifican isoformas distintas para este gen.
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