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Código SKU: E-AB-19961_120μL-ES
Anticuerpo policlonal GPT2, 120 μL
Este gen codifica una alanina transaminasa mitocondrial, una enzima piridoxal que cataliza la transaminación reversible entre alanina y 2-oxoglutarato para generar piruvato y glutamato. Las alanina transaminasas participan en la gluconeogénesis y el metabolismo de aminoácidos en numerosos tejidos, como el músculo esquelético, el riñón y el hígado. La activación del factor de transcripción 4 regula positivamente este gen en condiciones de estrés metabólico en líneas celulares de hepatocitos. Una mutación con pérdida de función en este gen se ha asociado con la encefalopatía del desarrollo. El empalme alternativo produce múltiples variantes de transcripción.
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