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Código SKU: E-AB-16118_120μL-ES
Anticuerpo policlonal FZD8, 120 μL
Este gen sin intrones pertenece a la familia de genes frizzled. Los miembros de esta familia codifican proteínas con siete dominios transmembrana que son receptores para la familia de proteínas de señalización del sitio de integración MMTV tipo Wingless. La mayoría de los receptores frizzled están acoplados a la vía de señalización canónica de la beta-catenina. Este gen presenta una alta expresión en dos líneas celulares de cáncer humano, lo que indica su posible papel en varios tipos de cáncer. Se ha determinado la estructura cristalina del dominio extracelular rico en cisteína de una proteína murina similar.
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