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Código SKU: E-AB-F1092M_100T×2-ES
Anticuerpo Elab Fluor® 647 anti-CD117/c-Kit de ratón [2B8], 100 T×2
El CD117 es un miembro de la superfamilia de inmunoglobulinas de 145 kD, también conocido como c-Kit y receptor del factor de células madre (SCFR). Es un receptor transmembrana de tirosina quinasa que se une al ligando c-Kit (también conocido como factor de acero, factor de células madre y factor de crecimiento de mastocitos). El CD117 se expresa en células madre hematopoyéticas (incluidas las células madre hematopoyéticas multipotentes, las células progenitoras comprometidas con linajes mieloides y/o eritroides, y los precursores de linfocitos T y B), mastocitos y células de leucemia mieloide aguda (LMA). La interacción del CD117 con su ligando es crucial para el desarrollo de las células madre hematopoyéticas.
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