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Código SKU: E-AB-18543_200μL-ES
Anticuerpo policlonal BPGM, 200 μL
El 2,3-difosfoglicerato (2,3-DPG) es una pequeña molécula presente en altas concentraciones en los glóbulos rojos, donde se une a la hemoglobina y disminuye su afinidad por el oxígeno. Este gen codifica una enzima multifuncional que cataliza la síntesis de 2,3-DPG mediante su actividad sintetasa y su degradación mediante su actividad fosfatasa. Esta enzima también posee actividad fosfoglicerato fosfomutasa. La deficiencia de esta enzima aumenta la afinidad de las células por el oxígeno. Las mutaciones en este gen provocan anemia hemolítica. Se han identificado múltiples variantes de empalme alternativo que codifican la misma proteína.
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