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Código SKU: E-AB-18889_200μL-ES
Anticuerpo policlonal BEX2, 200 μL
Este gen pertenece a la familia de genes ligados al cromosoma X que se expresan en el cerebro. La proteína codificada interactúa con el dominio LIM 2 del factor de transcripción en un complejo de unión al ADN que reconoce el elemento E-box y promueve la transcripción. Se ha descubierto que este gen es un supresor tumoral que se encuentra silenciado en el glioma humano. En células de cáncer de mama, este producto génico modula la apoptosis en respuesta al estrógeno y al tamoxifeno, y potencia el efecto antiproliferativo del tamoxifeno. Se han encontrado múltiples variantes de transcripción que codifican diferentes isoformas para este gen.
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