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Código SKU: E-AB-65234_120μL-ES
Anticuerpo policlonal ARL1, 120 μL
La proteína codificada por este gen pertenece a la familia de proteínas ARL (similares al factor de ribosilación de ADP), que están estructuralmente relacionadas con los factores de ribosilación de ADP (ARF). Los ARF, descritos como activadores de la actividad de la ADP-ribosiltransferasa de la toxina colérica (CT), regulan el tráfico intracelular a través de la membrana vesicular y estimulan una isoforma de la fosfolipasa D (PLD). Aunque inicialmente se creía que las proteínas ARL no activaban CT ni PLD, estudios posteriores demostraron que son estimuladores débiles de PLD y CT de forma dependiente de fosfolípidos. El empalme alternativo da lugar a múltiples variantes de transcripción que codifican diferentes isoformas.
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