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Código SKU: E-AB-13811_60μL-ES
Anticuerpo policlonal APLP1, 60 μL
Este gen codifica un miembro de la familia de genes de la proteína precursora amiloide, altamente conservada. La proteína codificada es una glicoproteína asociada a la membrana que se escinde mediante secretasas de forma similar a la escisión de la proteína precursora beta amiloide A4. Esta escisión libera un fragmento citoplasmático intracelular que puede actuar como activador transcripcional. La proteína codificada también puede participar en la maduración sináptica durante el desarrollo cortical. Se han descrito variantes de transcripción con empalme alternativo que codifican diferentes isoformas.
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