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Código SKU: E-AB-17831_20μL-ES
Anticuerpo policlonal APC, 20 μL
Este gen codifica una proteína supresora de tumores que actúa como antagonista de la vía de señalización Wnt. También participa en otros procesos, como la migración y adhesión celular, la activación transcripcional y la apoptosis. Los defectos en este gen causan poliposis adenomatosa familiar (PAF), una enfermedad premaligna autosómica dominante que suele progresar a malignidad. Las mutaciones asociadas a la enfermedad tienden a agruparse en una pequeña región denominada región de grupo de mutaciones (MCR) y dan lugar a un producto proteico truncado.
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