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Código SKU: E-AB-F1055E_100T×2-ES
Anticuerpo APC anti-CD11a humano [TS1/22.1.1.13], 100 T×2
CD11a es una glucoproteína transmembrana tipo I de 170-180 kD, también conocida como cadena LFA-1α y subunidad αL de la integrina. CD11a se asocia de forma no covalente con la integrina β2 (CD18) para formar LFA-1. Se expresa en todos los leucocitos, incluyendo linfocitos B y T, monocitos, macrófagos, neutrófilos, basófilos y eosinófilos. Está ausente en tejidos no hematopoyéticos y plaquetas. CD11a desempeña un papel fundamental en las interacciones leucocitarias y es importante en la coestimulación linfocitaria. CD11a/CD18 se une a ICAM-1 (CD54), ICAM-2 (CD102) e ICAM-3 (CD50).
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