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Código SKU: AN002340P_25μg-ES
Anticuerpo monoclonal alfa-sinucleína/SNCA (Captura), 25 μg
La alfa-sinucleína pertenece a la familia de las sinucleínas, que también incluye la beta-sinucleína y la gamma-sinucleína. Las sinucleínas se expresan abundantemente en el cerebro y ambas inhiben selectivamente la fosfolipasa D2. El SNCA puede contribuir a la integración de la señalización presináptica y el tráfico de membrana. Se han implicado defectos en el SNCA en la patogénesis de la enfermedad de Parkinson. Los péptidos del SNCA son un componente principal de las placas amiloides en el cerebro de pacientes con enfermedad de Alzheimer. Se han identificado cuatro transcripciones de empalme alternativo que codifican dos isoformas diferentes para este gen.
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