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Código SKU: E-AB-19802_200μL-ES
Anticuerpo policlonal ADGRE3, 200 μL
Este gen codifica un miembro de la familia de receptores transmembrana de siete tramos (TM7) de clase B, expresado predominantemente por células del sistema inmunitario. Los miembros de la familia se caracterizan por una extensa región extracelular con un número variable de dominios N-terminales similares al factor de crecimiento epidérmico (EGF), acoplados a un dominio TM7 mediante un dominio espaciador similar a la mucina. Este gen está estrechamente vinculado al gen que codifica la molécula similar al EGF que contiene el receptor 2 de la hormona similar a la mucina en el cromosoma 19. Esta proteína podría desempeñar un papel en las interacciones mieloide-mieloide durante las respuestas inmunitarias e inflamatorias. El empalme alternativo da lugar a múltiples variantes de transcripción que codifican diferentes isoformas.
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